Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889766 | 1.00 | MRGPRX4 (0.37) | MRGPRX4ALOX5APPOLBMAOBMAOA | |
| SCHEMBL6562969 | 0.89 | MRGPRX4 (0.34) | MRGPRX4POLBMAOBTDP1L3MBTL1 | |
| SCHEMBL6562973 | 0.89 | MRGPRX4 (0.34) | MRGPRX4POLBMAOBTDP1L3MBTL1 | |
| SCHEMBL6883872 | 0.86 | MRGPRX4 (0.34) | MRGPRX4ALOX5APTDP1 | |
| SCHEMBL6883874 | 0.86 | MRGPRX4 (0.34) | MRGPRX4ALOX5APTDP1 | |
| SCHEMBL6885431 | 0.84 | ALOX5AP (0.33) | ALOX5APMAOBMAOATDP1MAPK1 | |
| SCHEMBL6883924 | 0.84 | ALOX5AP (0.34) | MRGPRX4ALOX5APMAOBMAOATDP1 | |
| SCHEMBL6883929 | 0.84 | ALOX5AP (0.34) | MRGPRX4ALOX5APMAOBMAOATDP1 | |
| SCHEMBL6885428 | 0.84 | ALOX5AP (0.33) | ALOX5APMAOBMAOATDP1MAPK1 | |
| SCHEMBL6564840 | 0.81 | VDR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |