Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688170 | 0.86 | PTGER3 (0.41) | MAPTALDH1A1KDM4ESLC22A12SMN1; SMN2 | |
| SCHEMBL688216 | 0.86 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL688053 | 0.85 | PTGER3 (0.43) | MAPTALDH1A1KDM4ESLC22A12SMN1; SMN2 | |
| SCHEMBL686846 | 0.85 | PTGER3 (0.41) | MAPTALDH1A1SLC22A12SMN1; SMN2PTGER3 | |
| SCHEMBL688442 | 0.85 | PTGER3 (0.42) | MAPTSLC22A12PTGER3 | |
| SCHEMBL686896 | 0.84 | PTGER3 (0.44) | SLC22A12PTGER3 | |
| SCHEMBL688284 | 0.84 | PTGER3 (0.43) | MAPTALDH1A1KDM4ESLC22A12SMN1; SMN2 | |
| SCHEMBL29371834 | 0.84 | PTGER3 (0.44) | SLC22A12PTGER3 | |
| SCHEMBL688581 | 0.84 | PTGER3 (0.44) | KMT2AALDH1A1KDM4ESLC22A12SMN1; SMN2 | |
| SCHEMBL687687 | 0.84 | PTGER3 (0.38) | SLC22A12PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |