Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.57 |
| ▸ | CCR9 | P51686 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464529 | 0.91 | AR (0.69) | ARCCR9PDE10ACYP11B1KDM1A | |
| SCHEMBL6889022 | 0.81 | AR (0.68) | ARCYP11B1CYP11B2PTGDR2CYP19A1 | |
| SCHEMBL6889336 | 0.80 | AR (0.61) | ARCYP11B1KDM1ACYP11B2CYP19A1 | |
| SCHEMBL6464451 | 0.76 | AR (0.80) | ARCYP11B1KDM1ACYP11B2PTGDR2 | |
| SCHEMBL6468078 | 0.74 | AR (0.66) | ARCCR9CYP11B1KCNH2CYP11B2 | |
| SCHEMBL15147305 | 0.73 | AR (0.58) | ARCYP11B1CYP11B2PTGDR2 | |
| SCHEMBL6465291 | 0.73 | AR (1.00) | ARCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6466407 | 0.73 | AR (0.75) | ARCYP11B1CYP11B2PTGDR2CYP19A1 | |
| SCHEMBL6469502 | 0.73 | AR (0.75) | ARCYP11B1CYP11B2CYP19A1 | |
| SCHEMBL6468893 | 0.73 | AR (0.75) | ARCYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |