SCHEMBL6884497

SCHEMBL6884497

COCCOCC(COc1ccc(Cl)cc1)OC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
LMNA P02545 1/20 0.62
TSHR P16473 1/20 0.62
ALOX12 P18054 1/20 0.62
L3MBTL1 Q9Y468 2/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
CYP19A1 P11511 1/20 0.45
MAPK1 P28482 1/20 0.45
PPARG P37231 2/20 0.45
PPARA Q07869 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPT P10636 2/20 0.43
RAB9A P51151 2/20 0.43
UTS2R Q9UKP6 2/20 0.41
NPC1 O15118 1/20 0.40
SCN4A P35499 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11957653 0.83 MAPT (0.54) MEN1KMT2ALMNATSHRALOX12
SCHEMBL27250609 0.81 MAPK1 (0.43) MEN1KMT2ALMNATSHRALOX12
SCHEMBL6880910 0.81 MAPT (0.56) MEN1KMT2ALMNATSHRALOX12
SCHEMBL6882239 0.80 MTNR1A (0.48) MEN1KMT2ALMNAL3MBTL1ALDH1A1
SCHEMBL15385967 0.79 MEN1 (0.51) MEN1KMT2ALMNATSHRALOX12
SCHEMBL15385987 0.78 KMT2A (0.55) MEN1KMT2ALMNATSHRALOX12
SCHEMBL15385997 0.78 MEN1 (0.53) MEN1KMT2ALMNATSHRALOX12
SCHEMBL11957213 0.78 LMNA (0.53) MEN1KMT2ALMNATSHRALOX12
SCHEMBL7044454 0.77 PPARG (0.57) MEN1KMT2ALMNATSHRALOX12
SCHEMBL6936775 0.76 TSHR (0.52) MEN1KMT2ALMNATSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040260039-A1 Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin MITSUI CHEMICALS, INC. (JP) 2004-12-23 US disclosed
EP-0950649-B1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides MITSUI CHEMICALS INC (JP) 2003-03-26 EP disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed