SCHEMBL68845

SCHEMBL68845

Cc1ccc2c(c1)C(=O)C(Br)CS2

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
MAPT P10636 3/20 0.53
NPSR1 Q6W5P4 2/20 0.50
HTT P42858 2/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47
ACHE P22303 1/20 0.40
EPHX2 P34913 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
ELANE P08246 1/20 0.34
METAP1 P53582 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP19A1 P11511 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12240332 0.81 KDM4E (0.55) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL10959775 0.80 VHL (0.50) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL87047 0.80 KDM4E (0.53) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL30166143 0.80 VHL (0.50) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL11635690 0.76 KDM4E (0.56) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL9094355 0.75 S100A4 (0.35) KDM4EMAPTNPSR1LMNAHPGD
SCHEMBL69687 0.74 KDM4E (0.40) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL18434596 0.73 KDM4E (0.32) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL10562759 0.73 KDM4E (0.53) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL10561316 0.73 KDM4E (0.47) KDM4ESMN1; SMN2MAPTNPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-9878560-B2 Inkjet recording method using nozzle arrays and printed material obtained by the inkjet recording method FUJIFILM CORPORATION (JP) 2018-01-30 US disclosed
EP-2345703-B1 Inkjet ink composition and inkjet recording method FUJIFILM CORP (JP) 2017-09-13 EP disclosed
EP-2192163-B1 Ink composition and inkjet recording method FUJIFILM CORP (JP) 2017-04-19 EP disclosed
EP-2636709-B1 Actinic radiation-curing type ink set, inkjet recording method, and printed material FUJIFILM CORP (JP) 2017-04-05 EP disclosed
EP-2412765-B1 Inkjet recording method, and printed material FUJIFILM CORP (JP) 2017-01-18 EP disclosed
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
US-20090087576-A1 INK COMPOSITION FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042563-A1 Photocurable coating composition, and overprint and process for producing same FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20090081421-A1 PHOTOCURABLE COATING COMPOSITION, AND OVERPRINT AND PROCESS FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080239045-A1 INK SET FOR INKJET RECORDING AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
EP-1975210-A1 Ink set for inkjet recording and inkjet recording method FUJIFILM Corporation (JP) 2008-10-01 EP disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1944173-A1 Ink composition and inkjet recording method using the same FUJIFILM Corporation (JP) 2008-07-16 EP disclosed