SCHEMBL87047

SCHEMBL87047

BC1CSc2ccc(C)cc2C1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
MAPT P10636 3/20 0.53
NPSR1 Q6W5P4 2/20 0.50
HTT P42858 2/20 0.50
LMNA P02545 1/20 0.50
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47
ACHE P22303 1/20 0.40
CTSL P07711 1/20 0.36
EPHX2 P34913 1/20 0.36
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
ELANE P08246 1/20 0.34
METAP1 P53582 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12240332 0.81 KDM4E (0.55) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL68845 0.80 KDM4E (0.53) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL11635690 0.76 KDM4E (0.56) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL10562759 0.73 KDM4E (0.53) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL10561316 0.73 KDM4E (0.47) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL12240334 0.71 KDM4E (0.45) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL10054228 0.69 EPHX2 (0.49) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL9177744 0.69 KDM4E (0.49) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL67625 0.68 ACHE (0.44) KDM4ESMN1; SMN2MAPTNPSR1HTT
SCHEMBL56657 0.67 VHL (0.64) KDM4ESMN1; SMN2MAPTNPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8128843-B2 Photocurable composition, photocurable ink composition, process for producing photocured material, and inkjet recording method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20100015352-A1 INK-JET INK COMPOSITION, AND INK-JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed
US-20100015360-A1 AQUEOUS INK COMPOSITION, AQUEOUS INK COMPOSITION FOR INKJET RECORDING, AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed
US-20090186163-A1 PHOTOCURABLE COMPOSITION, PHOTOCURABLE INK COMPOSITION, PROCESS FOR PRODUCING PHOTOCURED MATERIAL, AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-07-23 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 KDM4E 679/4885SMN1; SMN2 2151/4885MAPT 2087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.