Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687862 | 0.90 | SMN1; SMN2 (0.43) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL688409 | 0.90 | PPARG (0.42) | ALDH1A1KDM4EHTTRXFP1NPSR1 | |
| SCHEMBL687096 | 0.86 | MEN1 (0.43) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL688605 | 0.85 | MEN1 (0.41) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL686624 | 0.85 | MEN1 (0.42) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL687874 | 0.84 | MAPT (0.44) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL687744 | 0.84 | PTGER3 (0.43) | RXFP1NPSR1TP53PTGER3MAPT | |
| SCHEMBL27587431 | 0.83 | MEN1 (0.41) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL687999 | 0.83 | SLC16A3 (0.42) | MEN1KMT2ANPSR1TP53SLC16A3 | |
| SCHEMBL687881 | 0.83 | PTGER3 (0.40) | RXFP1NPSR1TP53PTGER3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |