Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12810779 | 0.84 | HPGD (0.55) | SLC6A4SLC6A2HPGDKDM4EALDH1A1 | |
| SCHEMBL1415083 | 0.83 | LMNA (0.47) | SLC6A4SLC6A2HPGDKDM4EALDH1A1 | |
| SCHEMBL7011836 | 0.79 | CES2 (0.61) | SLC6A4HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL3302319 | 0.78 | CES2 (0.59) | HPGDKDM4EALDH1A1MAPTCES2 | |
| SCHEMBL458409 | 0.77 | NPSR1 (0.59) | HPGDKDM4EALDH1A1MCOLN3MAPT | |
| SCHEMBL22980975 | 0.76 | CES2 (0.57) | SLC6A4HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL7405569 | 0.76 | CES2 (0.47) | SLC6A4SLC6A2HPGDKDM4EALDH1A1 | |
| SCHEMBL759389 | 0.76 | CES2 (0.61) | SLC6A4SLC6A2HPGDKDM4EALDH1A1 | |
| SCHEMBL14052528 | 0.75 | HPGD (0.64) | HPGDALDH1A1MAPTLMNACES2 | |
| Hydrochloric Acid SCHEMBL3759428 | 0.75 | NPSR1 (0.57) | HPGDKDM4EALDH1A1MCOLN3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639130-B | Process for preparing fused imidazole compounds, rifumassiy reagent in stable form and process for preparing same | TAKAEDA CHEMICAL IND LTD | 2012-07-18 | — | — | CN | disclosed |
| CN-100588649-C | Prepare the method for condensed imidazole compound, reformatsky reagent having of stable form and preparation method thereof | TAKEDA CHEMICAL INDUSTRIES LTD | 2010-02-10 | — | — | CN | disclosed |
| CN-100572363-C | Imdazole derivatives, Its Preparation Method And Use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2009-12-23 | — | — | CN | disclosed |
| CN-1329394-C | Novel imidazole derivatives, process for producing the same and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2007-08-01 | — | — | CN | disclosed |
| CN-1923816-A | Method for producing condensed imidazole compound, reformatsky reagent having stable form and production thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2007-03-07 | — | — | CN | disclosed |
| CN-1900079-A | New imidazole derivative, method for producing the same and use of the same | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2007-01-24 | — | — | CN | disclosed |
| CN-1680336-A | New imidazole derivative, method for producing the same and use of the same | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-10-12 | — | — | CN | disclosed |
| CN-1639130-A | Process for preparing fused imidazole compounds, rifumassiy reagent in stable form and process for preparing same | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-07-13 | — | — | CN | disclosed |
| EP-1471056-A1 | PROCESS FOR PRODUCING FUSED IMIDAZOLE COMPOUND, REFORMATSKY REAGENT IN STABLE FORM, AND PROCESS FOR PRODUCING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |
| CN-1474819-A | Novel imidazole derivatives, process for producing the same and use thereof | ����ҩƷ��ҵ��ʽ���� | 2004-02-11 | — | — | CN | disclosed |