Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | BID | P55957 | 6/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771772 | 0.94 | TYR (0.41) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL6885297 | 0.91 | IAPP (0.36) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL7772060 | 0.86 | GABRA1 (0.41) | BIDMCL1BCL2L1BAK1IAPP | |
| SCHEMBL8077425 | 0.86 | TYR (0.45) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL6884343 | 0.84 | RPS6KB1 (0.40) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL8090927 | 0.78 | TYR (0.41) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL8085497 | 0.76 | TYR (0.47) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL6882798 | 0.76 | IAPP (0.38) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL14125673 | 0.72 | BID (0.45) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL28036103 | 0.71 | BID (0.47) | TYRBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442009-A1 | PRODUCTION OF KETO ACIDS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037846-A1 | PRODUCTION OF KETO ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | disclosed |