Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | BID | P55957 | 6/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.46 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.46 |
| ▸ | IAPP | P10997 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773989 | 0.82 | BID (0.47) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL8090927 | 0.82 | TYR (0.41) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL8077425 | 0.80 | TYR (0.45) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL27520237 | 0.79 | IDO1 (0.45) | TSHRMAPTALOX15MEN1TP53 | |
| SCHEMBL10620298 | 0.77 | BID (0.52) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL28788486 | 0.77 | BID (0.50) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL6885044 | 0.76 | TYR (0.41) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL7771772 | 0.76 | TYR (0.41) | TYRBIDMCL1BCL2L1BAK1 | |
| SCHEMBL10762942 | 0.76 | GABRA1 (0.53) | TSHRELANECTSGMAPTMEN1 | |
| SCHEMBL139993 | 0.76 | IAPP (0.67) | TYRBIDMCL1BCL2L1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831081-B1 | Production of aminophenols | CIBA SC HOLDING AG (CH) | 2000-11-02 | — | — | EP | disclosed |
| US-5908961-A | UNDER AQUEOUS ACIDIC CONDITIONS; CONTINUOUS MONITORING OFPH | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-06-01 | — | — | US | disclosed |
| EP-0831081-A1 | Production of aminophenols | Ciba SC Holding AG (CH) | 1998-03-25 | — | — | EP | disclosed |