Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27408743 | 0.89 | IDO1 (0.51) | IDO1TSHRCXCR2MAPTKMT2A | |
| SCHEMBL4840252 | 0.82 | IDO1 (0.45) | IDO1TSHRCXCR2MAPTKMT2A | |
| SCHEMBL4229462 | 0.82 | TSHR (0.48) | IDO1TSHRCXCR2MAPTKMT2A | |
| SCHEMBL25438138 | 0.81 | IDO1 (0.42) | IDO1TSHRCXCR2MAPTKMT2A | |
| SCHEMBL19214720 | 0.79 | IDO1 (0.43) | IDO1TSHRMAPTALDH1A1GAA | |
| SCHEMBL8573224 | 0.78 | IDO1 (0.41) | IDO1CXCR2MAPTKMT2AKDM4E | |
| SCHEMBL12649391 | 0.77 | IDO1 (1.00) | IDO1KMT2AMEN1GAA | |
| SCHEMBL11140267 | 0.77 | KDM4E (0.54) | TSHRCXCR2KMT2AKDM4EMEN1 | |
| SCHEMBL7773987 | 0.77 | IDO1 (0.41) | IDO1CXCR2MAPTKMT2AKDM4E | |
| SCHEMBL19334515 | 0.77 | MAPT (0.50) | IDO1MAPTKDM4EALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442009-A1 | PRODUCTION OF KETO ACIDS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037846-A1 | PRODUCTION OF KETO ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | disclosed |