Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885166 | 0.82 | IDO1 (0.62) | IDO1MAPK1POLBGAAKMT2A | |
| SCHEMBL27408743 | 0.76 | IDO1 (0.51) | IDO1MAPK1POLBGAAKMT2A | |
| SCHEMBL4229462 | 0.70 | TSHR (0.48) | IDO1GAAKMT2AMEN1CXCR2 | |
| SCHEMBL11140267 | 0.69 | KDM4E (0.54) | GAAKMT2AMEN1CXCR2LMNA | |
| SCHEMBL25438138 | 0.69 | IDO1 (0.42) | IDO1POLBGAAKMT2AMEN1 | |
| Catechol SCHEMBL28023341 | 0.69 | CA1 (0.49) | POLBGAAKMT2AMEN1LMNA | |
| SCHEMBL5323369 | 0.68 | HPGD (0.49) | MAPK1GAAKMT2AMEN1LMNA | |
| SCHEMBL5323373 | 0.68 | HPGD (0.49) | MAPK1GAAKMT2AMEN1LMNA | |
| SCHEMBL16333185 | 0.68 | TSHR (0.56) | POLBGAAKMT2AMEN1LMNA | |
| SCHEMBL19214720 | 0.68 | IDO1 (0.43) | IDO1MAPK1POLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449315-B2 | Bifunctional energy-reversible acyl-compositions | CRYOLIFE, INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20070167644-A1 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | CRYOLIFE, INC. (US) | 2007-07-19 | — | — | US | disclosed |
| EP-1392204-A4 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | CRYOLIFE INC (US) | 2007-07-18 | — | — | EP | disclosed |
| US-7157458-B2 | Bifunctional energy-reversible acyl-compositions | CRYOLIFE, INC. (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060106204-A1 | Bifunctional energy-reversible acyl-compositions | GILBERT CARL W | 2006-05-18 | — | — | US | disclosed |
| EP-1392204-A2 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | CryoLife, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| US-20020187993-A1 | Bifunctional energy-reversible acyl-compositions | CRYOLIFE, INC. | 2002-12-12 | — | — | US | disclosed |
| WO-2002083030-A2 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | CRYOLIFE, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020187993-A1 | Bifunctional energy-reversible acyl-compositions | ACACB, ACACA, ACAT1 | IDO1 2865/4885MAPK1 4838/4885POLB 1928/4885 |
| US-20070167644-A1 | BIFUNCTIONAL ENERGY-REVERSIBLE ACYL-COMPOSITIONS | ACACB, ACAT1, ACACA | IDO1 3019/4885MAPK1 4863/4885POLB 2055/4885 |
| US-20060106204-A1 | Bifunctional energy-reversible acyl-compositions | ACACB, ACAT1, ACACA | IDO1 3019/4885MAPK1 4863/4885POLB 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.