Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385988 | 0.85 | TSHR (0.58) | TSHRALDH1A1THRBTP53HSP90AA1 | |
| SCHEMBL48533 | 0.85 | TSHR (0.58) | TSHRALDH1A1THRBTP53HSP90AA1 | |
| SCHEMBL6884454 | 0.85 | POLB (0.42) | TSHRALDH1A1THRBSMN1; SMN2L3MBTL1 | |
| SCHEMBL10762934 | 0.82 | ALDH1A1 (0.49) | TSHRALDH1A1THRBCYP3A4ALOX15 | |
| SCHEMBL4229486 | 0.82 | IDO1 (0.42) | TSHRHSP90AA1L3MBTL1IDO1 | |
| SCHEMBL6885166 | 0.82 | IDO1 (0.62) | TSHRALDH1A1THRBTP53TDP1 | |
| SCHEMBL21116058 | 0.81 | TRPA1 (0.41) | TSHRALDH1A1THRBTP53TDP1 | |
| SCHEMBL104062 | 0.79 | IDO1 (0.59) | TSHRALDH1A1THRBTP53CYP3A4 | |
| SCHEMBL13303751 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1THRBTP53HSP90AA1 | |
| SCHEMBL14930874 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1THRBTP53HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660884-B1 | CROWN ETHER DERIVATIVES | LIFE TECHNOLOGIES CORP (US) | 2012-05-23 | — | — | EP | disclosed |
| US-7498467-B2 | Antioxidant and bisaminophenol derivative | IDEMITSU KOSAN CO., LTD. (JP) | 2009-03-03 | — | — | US | disclosed |
| US-20080161608-A1 | ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE | IDEMITSU KOSAN CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20060208227-A1 | Antioxidant and bisaminophenol derivative | IDEMITSU LOSAN CO., LTD (JP) | 2006-09-21 | — | — | US | disclosed |
| EP-1612254-A1 | ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161608-A1 | ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE | CBR1, CBR3, HMOX1 | TSHR 2375/4885ALDH1A1 204/4885THRB 2390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.