Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886751 | 0.97 | BCHE (0.54) | BCHEKDM4ESMN1; SMN2CHRM2MEN1 | |
| SCHEMBL6881441 | 0.90 | BCHE (0.51) | BCHEKDM4ESMN1; SMN2CHRM2MEN1 | |
| SCHEMBL7048973 | 0.88 | BCHE (0.52) | BCHEKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL6883442 | 0.86 | BCHE (0.52) | BCHEKDM4ESMN1; SMN2CHRM2MEN1 | |
| SCHEMBL2107020 | 0.85 | CYP4F2 (0.46) | BCHEMEN1KMT2A | |
| SCHEMBL6887560 | 0.85 | BCHE (0.53) | BCHEKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL6155482 | 0.82 | BCHE (0.49) | BCHEKDM4ESMN1; SMN2CHRM2TP53 | |
| SCHEMBL6156190 | 0.81 | BCHE (0.48) | BCHEKDM4ESMN1; SMN2CHRM2MEN1 | |
| SCHEMBL6155828 | 0.79 | BCHE (0.50) | BCHEKDM4ESMN1; SMN2CHRM2TP53 | |
| SCHEMBL6886826 | 0.79 | RRM1 (0.47) | BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |