SCHEMBL2107020

SCHEMBL2107020

CC(C)(O)CCCCc1cccc(OCc2ccc(C(O)O)cc2)c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
MGLL Q99685 1/20 0.44
PPARA Q07869 5/20 0.43
PPARG P37231 4/20 0.43
SMPD1 P17405 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
BCHE P06276 3/20 0.41
FFAR1 O14842 1/20 0.40
APP P05067 1/20 0.40
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6885228 0.85 BCHE (0.53) MEN1KMT2ABCHE
SCHEMBL6886751 0.84 BCHE (0.54) MEN1KMT2ABCHE
SCHEMBL6155587 0.82 CYSLTR2 (0.44) MEN1KMT2ABCHEFFAR1APP
SCHEMBL6155248 0.82 CYSLTR2 (0.42) MEN1KMT2ABCHEFFAR1APP
SCHEMBL2107635 0.81 MGLL (0.46) CYP4F2CYP4A11MGLLPPARAPPARG
SCHEMBL6155493 0.81 APP (0.44) APPNR4A1NR4A2NR4A3
SCHEMBL2107016 0.80 VDR (0.48) CYP4F2CYP4A11MGLLPPARAPPARG
SCHEMBL6155835 0.80 APP (0.44) APPNR4A1NR4A2NR4A3
SCHEMBL6155489 0.79 NR4A2 (0.42) SMPD1NR4A1NR4A2NR4A3
SCHEMBL6886826 0.79 RRM1 (0.47) MEN1KMT2ABCHEAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP claimed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US claimed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP claimed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO claimed
US-11730682-B2 Self-standing cosmetic sheet L'OREAL (FR) 2023-08-22 US disclosed
EP-2836187-B1 SELF-STANDING COSMETIC SHEET OREAL (FR) 2021-12-08 EP disclosed
US-20180235849-A1 SELF-STANDING COSMETIC SHEET L'OREAL (FR) 2018-08-23 US disclosed
US-9949897-B2 Self-standing cosmetic sheet L'OREAL (FR) 2018-04-24 US disclosed
US-20150209243-A1 SELF-STANDING COSMETIC SHEET L'OREAL (FR) 2015-07-30 US disclosed
EP-1658838-B1 Emulsification system for use in cosmetics ORÉAL L (FR) 2014-07-02 EP disclosed
US-8158136-B2 Emulsification system for use in cosmetics L'ORÉAL (FR) 2012-04-17 US disclosed
US-20070025937-A1 Cosmetic compositions containing hydroquinone L'OREAL S.A. (FR) 2007-02-01 US disclosed
US-20050169945-A1 Composition for protecting keratin material, process of making, uses thereof L'OREAL (FR) 2005-08-04 US disclosed
EP-1559398-A1 Process for preparing a composition for the cosmetic treatment of keratinous materials on the basis of a pressurised fluid and vitamins L'OREAL (FR) 2005-08-03 EP disclosed
EP-1124779-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2005-02-02 EP disclosed
US-6689922-B1 BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) 2004-02-10 US disclosed
US-20020197289-A1 Compositions and methods for combating the appearance of ageing L'OREAL (FR) 2002-12-26 US disclosed
EP-1262168-A1 Composition containing fibres to combat the skin aging process L'OREAL (FR) 2002-12-04 EP disclosed
EP-1124779-A1 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2001-08-22 EP disclosed
WO-2000026167-A1 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2000-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020197289-A1 Compositions and methods for combating the appearance of ageing CYP24A1, CYP27B1, CYP2R1 CYP4F2 60/4885CYP4A11 123/4885MGLL 1535/4885
US-20150209243-A1 SELF-STANDING COSMETIC SHEET CUTA, SUCLG1, SIGLEC7 CYP4F2 4804/4885CYP4A11 4810/4885MGLL 499/4885
US-20180235849-A1 SELF-STANDING COSMETIC SHEET CUTA, DSG1, SUCLG1 CYP4F2 4281/4885CYP4A11 4206/4885MGLL 459/4885
US-11730682-B2 Self-standing cosmetic sheet CUTA, DSG1, SUCLG1 CYP4F2 4281/4885CYP4A11 4206/4885MGLL 459/4885
US-20050169945-A1 Composition for protecting keratin material, process of making, uses thereof KRT18, PROC, CUTA CYP4F2 1050/4885CYP4A11 2282/4885MGLL 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.