Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885241 | 1.00 | BACE1 (0.36) | BACE1PTGS1PTGS2VDRTTR | |
| SCHEMBL6885232 | 1.00 | BACE1 (0.36) | BACE1PTGS1PTGS2VDRTTR | |
| SCHEMBL6156483 | 0.92 | VDR (0.38) | BACE1VDR | |
| SCHEMBL6888552 | 0.92 | VDR (0.38) | BACE1VDR | |
| SCHEMBL6888549 | 0.92 | VDR (0.38) | BACE1VDR | |
| SCHEMBL6886921 | 0.84 | VDR (0.41) | BACE1VDR | |
| SCHEMBL6158573 | 0.84 | VDR (0.41) | BACE1VDR | |
| SCHEMBL6886918 | 0.84 | VDR (0.41) | BACE1VDR | |
| SCHEMBL6885664 | 0.83 | VDR (0.40) | VDR | |
| SCHEMBL6155757 | 0.83 | VDR (0.48) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |