SCHEMBL6888552

CCC(O)(C=CC=C(C)c1cccc(C=Cc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)c1)CC

nearest known ligand 0.38

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	VDR	P11473	2/20	0.38

▸	BACE1	P56817	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6156483	1.00	VDR (0.38)	VDRBACE1
SCHEMBL6888549	1.00	VDR (0.38)	VDRBACE1
SCHEMBL6885237	0.92	BACE1 (0.36)	VDRBACE1
SCHEMBL6885241	0.92	BACE1 (0.36)	VDRBACE1
SCHEMBL6885232	0.92	BACE1 (0.36)	VDRBACE1
SCHEMBL6887847	0.85	VDR (0.42)	VDR
SCHEMBL6887842	0.85	VDR (0.42)	VDR
SCHEMBL6155582	0.85	VDR (0.42)	VDR
SCHEMBL6881388	0.84	VDR (0.49)	VDR
SCHEMBL6881384	0.84	VDR (0.49)	VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6689922-B1	BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION	GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR)	2004-02-10	—	—	US	disclosed