Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 6/20 | 0.34 |
| ▸ | CTRC | Q99895 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6385317 | 0.90 | F2 (0.40) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL8203321 | 0.86 | F2 (0.37) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL14538267 | 0.85 | F2 (0.40) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL6886996 | 0.85 | F2 (0.37) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL6888168 | 0.82 | F2 (0.37) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL15580091 | 0.81 | ITGB3 (0.41) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL12831634 | 0.81 | F2 (0.39) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL6124837 | 0.81 | F2 (0.40) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL6886505 | 0.81 | F2 (0.38) | F2PRSS1CMA1CTRCACE | |
| SCHEMBL12831782 | 0.80 | ITGB3 (0.40) | F2PRSS1CMA1CTRCACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002808-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| WO-2009082701-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2009-07-02 | — | — | WO | disclosed |