Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 4/20 | 0.35 |
| ▸ | CTRC | Q99895 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6385317 | 0.90 | F2 (0.40) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL6124837 | 0.89 | F2 (0.40) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL12831634 | 0.88 | F2 (0.39) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL13563948 | 0.88 | ITGB3 (0.40) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL8203250 | 0.87 | F2 (0.41) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL6124816 | 0.87 | F2 (0.44) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL13436021 | 0.85 | F2 (0.43) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL13564331 | 0.85 | F2 (0.41) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL13564316 | 0.84 | MMP2 (0.40) | ITGB3ITGA2BF2PRSS1CMA1 | |
| SCHEMBL13071447 | 0.83 | F2 (0.44) | ITGB3ITGA2BF2PRSS1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038293-A1 | CYCLIC PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-31 | — | — | WO | disclosed |