SCHEMBL688568

SCHEMBL688568

O=C(Br)CCCCC(=O)Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
TSHR P16473 4/20 0.41
NFKB1 P19838 2/20 0.41
PMP22 Q01453 1/20 0.41
SLC22A6 Q4U2R8 2/20 0.35
CES2 O00748 4/20 0.35
CES1 P23141 4/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
GPR84 Q9NQS5 4/20 0.33
FFAR1 O14842 2/20 0.33
FFAR4 Q5NUL3 2/20 0.33
AKR1B1 P15121 1/20 0.33
CYP2D6 P10635 1/20 0.33
FOLH1 Q04609 1/20 0.33
PPARG P37231 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL688573 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL689631 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL689502 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL11419325 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL689239 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL16429437 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL689053 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL11419333 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL718865 0.96 TSHR (0.47) LMNATSHRNFKB1PMP22SLC22A6
SCHEMBL809396 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112552803-B Antibacterial coil coating with water resistance 广东碧橙材料科技有限公司 2021-08-27 CN claimed
CN-112592468-B Preparation process of flame-retardant polyester resin and application of flame-retardant polyester resin in flame-retardant coating 宁波顺声通讯设备有限公司 2021-08-27 CN claimed
CN-112592468-A Preparation process of flame-retardant polyester resin and application of flame-retardant polyester resin in flame-retardant coating 吴春秋 2021-04-02 CN claimed
CN-112552803-A Antibacterial coil coating with water resistance 吴春秋 2021-03-26 CN claimed
EP-3362439-B1 BIOMASS-DERIVED POLYMERS AND COPOLYMERS INCORPORATING MONOLIGNOLS AND THEIR DERIVATIVES UNIV CALIFORNIA (US) 2024-12-04 EP disclosed
CN-109789645-B Method for producing reinforced polyamides by extrusion 巴斯夫欧洲公司 2022-08-16 CN disclosed
CN-112552803-B Antibacterial coil coating with water resistance 广东碧橙材料科技有限公司 2021-08-27 CN disclosed
CN-112592468-B Preparation process of flame-retardant polyester resin and application of flame-retardant polyester resin in flame-retardant coating 宁波顺声通讯设备有限公司 2021-08-27 CN disclosed
CN-112592468-A Preparation process of flame-retardant polyester resin and application of flame-retardant polyester resin in flame-retardant coating 吴春秋 2021-04-02 CN disclosed
CN-112552803-A Antibacterial coil coating with water resistance 吴春秋 2021-03-26 CN disclosed
US-10941104-B2 Biomass-derived polymers and copolymers incorporating monolignols and their derivatives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-03-09 US disclosed
CN-109312020-B Method for producing aminomethylated bead polymers 朗盛德国有限责任公司 2021-03-05 CN disclosed
US-4252529-A AMINOPHENOL OR AMINONAPHTHOL COMPOUND WITH SUBSTITUTED FIBER-REACTIVE RADICAL HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed
US-4217436-A N,N*-HYDROCARBYLENEDICARBONYLBIS/CYCLIC UREA/ THE UPJOHN COMPANY (US) 1980-08-12 US disclosed
US-4212964-A FOR ADHESIVES PHILLIPS PETROLEUM COMPANY (US) 1980-07-15 US disclosed
US-4190599-A ACRYLATE COPOLYMER AND EPOXY RESIN THE UPJOHN COMPANY (US) 1980-02-26 US disclosed
US-4138398-A Bis-cyclic ureas THE UPJOHN COMPANY (US) 1979-02-06 US disclosed
US-4104233-A VINYL HALIDE POLYMERS, SMOKE AND FIRE RETARDANTS MONSANTO COMPANY (US) 1978-08-01 US disclosed
US-4051087-A LAMINATES, ADHESIVES PHILLIPS PETROLEUM COMPANY (US) 1977-09-27 US disclosed
US-4008168-A Polybutene composition containing halogen-containing additives and use thereof STANDARD OIL COMPANY (INDIANA) (US) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10941104-B2 Biomass-derived polymers and copolymers incorporating monolignols and their derivatives PAOX, CBX4, COASY LMNA 375/4885TSHR 4868/4885NFKB1 3252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.