SCHEMBL718865

SCHEMBL718865

O=C(Br)CCCCCCCC(=O)Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
LMNA P02545 3/20 0.47
NFKB1 P19838 1/20 0.47
PMP22 Q01453 1/20 0.47
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
GPR84 Q9NQS5 7/20 0.38
CES2 O00748 3/20 0.38
CES1 P23141 3/20 0.38
FFAR1 O14842 2/20 0.38
FFAR4 Q5NUL3 2/20 0.38
PPARG P37231 6/20 0.36
PPARD Q03181 6/20 0.36
PPARA Q07869 6/20 0.36
HDAC11 Q96DB2 5/20 0.36
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419325 1.00 TSHR (0.47) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL688573 1.00 TSHR (0.47) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL689502 1.00 TSHR (0.47) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL689631 1.00 TSHR (0.47) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL689239 1.00 TSHR (0.47) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL11419333 1.00 TSHR (0.47) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL16429437 1.00 TSHR (0.47) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL689053 1.00 TSHR (0.47) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL688568 0.96 LMNA (0.44) TSHRLMNANFKB1PMP22HDAC3
SCHEMBL809396 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3362439-B1 BIOMASS-DERIVED POLYMERS AND COPOLYMERS INCORPORATING MONOLIGNOLS AND THEIR DERIVATIVES UNIV CALIFORNIA (US) 2024-12-04 EP disclosed
US-9321017-B2 Gas-separation membrane NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2016-04-26 US disclosed
US-20150033945-A1 GAS-SEPARATION MEMBRANE NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2015-02-05 US disclosed
US-8222446-B2 Method for producing dihydroxybenzene derivative MITSUI CHEMICALS, INC. (JP) 2012-07-17 US disclosed
EP-1820667-B1 PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2012-02-29 EP disclosed
US-20110004013-A1 METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE MITSUI CHEMICALS, INC. (JP) 2011-01-06 US disclosed
EP-2269976-A1 PROCESS FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE Mitsui Chemicals, Inc. (JP) 2011-01-05 EP disclosed
US-7823614-B2 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2010-11-02 US disclosed
US-20090229728-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-09-17 US disclosed
EP-1820667-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-08-22 EP disclosed
EP-0062220-B1 STABILIZED COAL-OIL MIXTURE DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1985-02-13 EP disclosed
US-4389219-A POLYETHER-POLYIMINE ADDUCT DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1983-06-21 US disclosed
EP-0062220-A2 Stabilized coal-oil mixture DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1982-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110004013-A1 METHOD FOR PRODUCING DIHYDROXYBENZENE DERIVATIVE UBE2B, UBE2G2, TUBB2B TSHR 2733/4885LMNA 3340/4885NFKB1 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.