SCHEMBL68859

SCHEMBL68859

CC1CC(=O)c2ccccc2S1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
KDM4E B2RXH2 5/20 0.57
BRD4 O60885 1/20 0.53
CREBBP Q92793 1/20 0.53
HPGD P15428 4/20 0.51
KLK7 P49862 1/20 0.51
GSK3B P49841 2/20 0.47
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
SIGMAR1 Q99720 1/20 0.43
S100A4 P26447 1/20 0.40
ACHE P22303 1/20 0.40
POLB P06746 1/20 0.39
TSHR P16473 3/20 0.37
HSD17B10 Q99714 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
AR P10275 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373688 0.77 SIGMAR1 (0.43) ALDH1A1KDM4EBRD4CREBBPHPGD
SCHEMBL8817667 0.77 SMN1; SMN2 (0.56) ALDH1A1KDM4EHPGDGSK3BSIGMAR1
SCHEMBL10814919 0.77 SIGMAR1 (0.47) ALDH1A1KDM4EBRD4CREBBPHPGD
SCHEMBL28814207 0.77 SIGMAR1 (0.43) ALDH1A1KDM4EBRD4CREBBPHPGD
SCHEMBL10381879 0.77 SIGMAR1 (0.47) ALDH1A1KDM4EBRD4CREBBPHPGD
SCHEMBL10383073 0.77 KDM4E (0.55) ALDH1A1KDM4EBRD4CREBBPHPGD
SCHEMBL8474208 0.77 SIGMAR1 (0.41) ALDH1A1KDM4EBRD4CREBBPHPGD
SCHEMBL12240274 0.77 KDM4E (0.55) ALDH1A1KDM4EBRD4CREBBPHPGD
SCHEMBL9143961 0.76 ALDH1A1 (0.41) ALDH1A1KDM4EBRD4CREBBPHPGD
SCHEMBL9819297 0.75 KDM4E (0.54) ALDH1A1KDM4EBRD4CREBBPHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
US-12037501-B2 Photocurable ink composition and image recording method FUJIFILM CORPORATION (JP) 2024-07-16 US disclosed
EP-3689981-B1 ACTINIC-RAY-CURABLE INK-JET INK, LIGHT-SHIELDING FILM, AND PRODUCTION METHOD FOR LIGHT-SHIELDING FILM FUJIFILM CORP (JP) 2024-07-10 EP disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
US-20230142929-A1 INK SET AND PRINTED ARTICLE FUJIFILM CORPORATION (JP) 2023-05-11 US disclosed
EP-3475260-B1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR UNIV KONSTANZ (DE) 2022-03-30 EP disclosed
EP-3950856-A1 PHOTOCURABLE INK COMPOSITION AND METHOD FOR IMAGE RECORDING FUJIFILM Corporation (JP) 2022-02-09 EP disclosed
WO-2022015624-A1 SUBSTITUTED DIHYDROPYRAZINEDIONES AS MODULATORS OF THE NMDA RECEPTOR SCHRÖDINGER, INC. (US) 2022-01-20 WO disclosed
US-20210395549-A1 PHOTOCURABLE INK COMPOSITION AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2021-12-23 US disclosed
CN-110698456-B Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof 重庆医药高等专科学校 2021-05-14 CN disclosed
WO-1990001482-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1990-02-22 WO disclosed
EP-0354694-A1 Therapeutic [1]benzothiopyrano[4,3-c]pyrazoles The Boots Company PLC (GB) 1990-02-14 EP disclosed
US-4853410-A Hydroxyacetic acid derivatives for the treatment of diabetic complications PFIZER INC. (US) 1989-08-01 US disclosed
WO-1987004344-A1 HYDROXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETIC COMPLICATIONS PFIZER INC. (US) 1987-07-30 WO disclosed
EP-0230379-A2 Chroman- and thiochroman-4-acetic acids useful in the treatment of diabetic complications PFIZER INC. (US) 1987-07-29 EP disclosed
US-4198426-A 2-Substituted-3-methyl-γ-pyrone tricyclic derivatives AYERST MCKENNA & HARRISON LTD. (CA) 1980-04-15 US disclosed
US-4189490-A 2-Substituted-3-methyl-γ-pyrone tricyclic derivatives AYERST MCKENNA & HARRISON LIMITED (CA) 1980-02-19 US disclosed
US-4177284-A 2-Substituted-3-methyl-γ-pyrone tricvclic derivatives and process therefor AYERST MCKENNA & HARRISON LTD. (CA) 1979-12-04 US disclosed
US-4105778-A ANTIALLERGENS, BACTERICIDES, FUNGICIDES AYERST, MCKENNA & HARRISON, LTD. (CA) 1978-08-08 US disclosed
US-4060619-A ANTIALLERGY, MICROBIOCIDE AYERST MCKENNA AND HARRISON LTD. (CA) 1977-11-29 US disclosed