Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017027 | 0.84 | TBXA2R (0.48) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL1654173 | 0.83 | PTGDR2 (0.51) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL1654175 | 0.83 | PTGDR2 (0.51) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL1012449 | 0.79 | PTGDR2 (0.58) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL1009852 | 0.79 | PTGDR2 (0.58) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL6016813 | 0.78 | EGFR (0.46) | RAB9AMMP1MMP2MMP9EGFR | |
| SCHEMBL2008263 | 0.77 | PTGDR2 (0.56) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL2008264 | 0.77 | PTGDR2 (0.56) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL6016918 | 0.77 | EGFR (0.38) | KMT2ALMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27634913 | 0.75 | MTOR (0.47) | TSHRALDH1A1NPSR1PTGDR2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471057-A1 | Pyrimidinylacetic acid derivatives useful for the treatment of diseases mediated by CRTH2 | Bayer HealthCare AG (DE) | 2004-10-27 | — | — | EP | claimed |