Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881308 | 0.88 | L3MBTL1 (0.48) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL872421 | 0.84 | HTR1A (0.61) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL3959610 | 0.84 | MAOB (0.51) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL27090052 | 0.83 | L3MBTL1 (0.51) | L3MBTL1LMNAHTR1ADRD2MAPT | |
| SCHEMBL6885785 | 0.82 | PTGER1 (0.49) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL11840264 | 0.81 | L3MBTL1 (0.49) | L3MBTL1LMNAHTR1ADRD2MAPT | |
| SCHEMBL2394733 | 0.80 | L3MBTL1 (0.48) | L3MBTL1LMNAHTR1ADRD2MAPT | |
| SCHEMBL30523700 | 0.80 | L3MBTL1 (0.48) | L3MBTL1LMNAHTR1ADRD2MAPT | |
| SCHEMBL1654686 | 0.80 | L3MBTL1 (0.48) | L3MBTL1LMNAHTR1ADRD2MAPT | |
| SCHEMBL2394736 | 0.80 | L3MBTL1 (0.48) | L3MBTL1LMNAHTR1ADRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |