Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155828 | 0.91 | BCHE (0.50) | VDRBCHE | |
| SCHEMBL2107016 | 0.88 | VDR (0.48) | VDRBCHECYP4F2CYP4A11NOS1 | |
| SCHEMBL6155482 | 0.88 | BCHE (0.49) | VDRBCHE | |
| SCHEMBL6155122 | 0.80 | VDR (0.48) | VDRBCHE | |
| SCHEMBL6156099 | 0.78 | VDR (0.48) | VDRBCHE | |
| SCHEMBL6156495 | 0.77 | BCHE (0.49) | BCHE | |
| SCHEMBL6155571 | 0.77 | VDR (0.46) | VDRBCHE | |
| SCHEMBL6155831 | 0.76 | VDR (0.46) | VDRNOS1NOS2 | |
| SCHEMBL6155485 | 0.75 | VDR (0.45) | VDRNOS1NOS2 | |
| SCHEMBL6155289 | 0.74 | VDR (0.46) | VDRBCHENOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |