Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155831 | 0.97 | VDR (0.46) | VDRAPPMTNR1AMTNR1BNOS1 | |
| SCHEMBL6156102 | 0.90 | VDR (0.48) | VDRAPPMTNR1AMTNR1BNOS1 | |
| SCHEMBL6155129 | 0.87 | VDR (0.48) | VDRAPPMTNR1AMTNR1BNOS1 | |
| SCHEMBL6156203 | 0.86 | MTNR1A (0.42) | APPMTNR1AMTNR1BBCL2 | |
| SCHEMBL6155289 | 0.84 | VDR (0.46) | VDRAPPNOS1NOS2BCL2 | |
| SCHEMBL6156500 | 0.83 | MTNR1A (0.42) | APPMTNR1AMTNR1BBCL2 | |
| SCHEMBL6155493 | 0.82 | APP (0.44) | APPMTNR1AMTNR1BBCL2 | |
| SCHEMBL2107016 | 0.81 | VDR (0.48) | VDRNOS1NOS2 | |
| SCHEMBL6156207 | 0.79 | MTNR1A (0.42) | APPMTNR1AMTNR1BBCL2 | |
| SCHEMBL6155835 | 0.79 | APP (0.44) | APPMTNR1AMTNR1BBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | claimed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | claimed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |