Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884914 | 0.83 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6876889 | 0.83 | ADORA2A (0.64) | ADORA2A | |
| SCHEMBL6885011 | 0.81 | ADORA2A (0.47) | DHODHADORA2APARP1GAA | |
| SCHEMBL6883012 | 0.81 | ADORA2A (0.44) | ADORA2A | |
| SCHEMBL6882934 | 0.81 | ADORA2A (0.67) | DHODHADORA2APARP1GAA | |
| SCHEMBL6886917 | 0.81 | ADORA2A (0.67) | DHODHADORA2APARP1GAA | |
| SCHEMBL989656 | 0.80 | ADORA2A (0.70) | ADORA2A | |
| SCHEMBL6885163 | 0.79 | ADORA2A (0.73) | ADORA2A | |
| SCHEMBL22722580 | 0.79 | ADORA2A (0.58) | DHODHADORA2APARP1GAA | |
| SCHEMBL6887176 | 0.79 | ADORA2A (0.60) | DHODHADORA2APARP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689790-B2 | 8-AMINO-6-AMIDO-SUBSTITUTED-(1,2,4)TRIAZOLO(1,5-A)PYRIDINES; ADENOSINE RECEPTOR MODULATERS | HOFFMANN-LA ROCHE INC. | 2004-02-10 | — | — | US | disclosed |