Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | ACLY | P53396 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL28292303 | 0.94 | THRB (0.70) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| Fluoromethane SCHEMBL11207274 | 0.94 | THRB (0.70) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| SCHEMBL37922 | 0.94 | THRB (0.78) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| SCHEMBL31083846 | 0.94 | THRB (0.78) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| Methyl Alcohol SCHEMBL29185037 | 0.92 | THRB (0.84) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| Fluoride SCHEMBL648538 | 0.91 | THRB (0.74) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL11050684 | 0.91 | THRB (0.74) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| SCHEMBL10694667 | 0.91 | THRB (0.74) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL808878 | 0.91 | THRB (0.74) | THRBACLYALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3086542 | 0.91 | THRB (0.74) | THRBACLYALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118072956-A | Biomarker combination for predicting adult stage metabolism related fatty liver disease incidence risk from childhood, screening method and prediction system thereof | 中国医学科学院北京协和医院 | 2024-05-24 | — | — | CN | disclosed |
| CN-117731677-A | Compound preparation and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-106748712-A | The preparation method of hyptafluorobutyric acid and its derivative | 阜新瑞宁化工有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-104678002-A | Biomarker for evaluating lung cancer disease | UNIV SHENYANG PHARMACEUTICAL | 2015-06-03 | — | — | CN | disclosed |
| CN-104678035-A | Application of plasma as liver cancer diagnostic marker | UNIV SHENYANG PHARMACEUTICAL | 2015-06-03 | — | — | CN | disclosed |
| CN-104677998-A | Novel biomarker for evaluating lung cancer disease through plasma | UNIV SHENYANG PHARMACEUTICAL | 2015-06-03 | — | — | CN | disclosed |
| CN-104677999-A | Biomarker for recognizing liver cancer and lung cancer through plasma | UNIV SHENYANG PHARMACEUTICAL | 2015-06-03 | — | — | CN | disclosed |
| CN-104678003-A | Biomarker for evaluating liver cancer disease by using urine | UNIV SHENYANG PHARMACEUTICAL | 2015-06-03 | — | — | CN | disclosed |
| CN-104678037-A | Biomarker for differentiating liver cancers from lung cancers | UNIV SHENYANG PHARMACEUTICAL | 2015-06-03 | — | — | CN | disclosed |
| EP-1426381-A1 | An epithelial protein and DNA thereof for use in early cancer detection | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6500625-B1 | PURIFIED AND ISOLATED EPITHELIAL PROTEIN, PEPTIDE AND VARIANTS THEREOF WHOSE INCREASED PRESENCE IN AN EPITHELIAL CELL IS INDICATIVE OF PRECANCER. ONE EPITHELIAL PROTEIN WHICH IS AN EARLY DETECTION MARKER FOR LUNG CANCER WAS PURIFIED FROM TWO | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2002-12-31 | — | — | US | disclosed |
| US-6251586-B1 | DETECTING CELLS EXPRESSING PREFERENTIAL HETEROGENOUS RIBONUCLEOPROTEIN; INCUBATE CELL WITH PROBES, ILLUMINATE CELLS, USE COMPUTER TO DEVELOP IMAGES AND COMPARE TO CONTROL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-06-26 | — | — | US | disclosed |
| US-5994062-A | DETECTING MESSENGER RNA ENCODING A HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN PEPTIDE BY ISOLATING EPITHIAL CELLS, MIXING RNA FROM THE CELLS WITH A PROBE ENCODING A MARKER PROTEIN, FORMING A HYBRIDIZATION PRODUCT IN AN IMMUNOASSAY KIT | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0861323-A1 | AN EPITHELIAL PROTEIN AND DNA THEREOF FOR USE IN EARLY CANCER DETECTION | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1998014469-A2 | AN EPITHELIAL PROTEIN AND DNA THEREOF FOR USE IN EARLY CANCER DETECTION | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-04-09 | — | — | WO | disclosed |