Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PKLR | P30613 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112930 | 0.87 | KMT2A (0.67) | HTTGAAALDH1A1KDM4ELMNA | |
| SCHEMBL22080777 | 0.86 | ALDH1A1 (0.70) | GAAALDH1A1KDM4EL3MBTL1MAPK1 | |
| SCHEMBL22032773 | 0.86 | KMT2A (0.59) | USP2HTTGAANPSR1ALDH1A1 | |
| SCHEMBL4112800 | 0.85 | ALDH1A1 (0.65) | HTTGAAALDH1A1KDM4ELMNA | |
| SCHEMBL17100765 | 0.84 | MAPT (0.58) | USP2HTTALDH1A1KDM4ELMNA | |
| SCHEMBL16788114 | 0.84 | HTT (0.69) | USP2HTTGAANPSR1ALDH1A1 | |
| SCHEMBL8218729 | 0.83 | LMNA (0.53) | USP2HTTGAANPSR1ALDH1A1 | |
| SCHEMBL12459445 | 0.82 | ALDH1A1 (0.56) | HTTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12209246 | 0.82 | HTT (0.66) | USP2HTTGAANPSR1ALDH1A1 | |
| SCHEMBL1472052 | 0.81 | USP2 (0.77) | USP2HTTGAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444203-A1 | CANNABINOID RECEPTOR LIGANDS | Schering Corporation (US) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003042174-A1 | CANNABINOID RECEPTOR LIGANDS | SCHERING CORPORATION (US) | 2003-05-22 | — | — | WO | disclosed |