SCHEMBL688742

SCHEMBL688742

CCc1ccc(OC(=O)/C=C/c2ccc(OC)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.62
MEN1 O00255 2/20 0.62
MAPT P10636 1/20 0.62
GSK3B P49841 1/20 0.59
F3 P13726 2/20 0.58
POLB P06746 1/20 0.57
THRB P10828 1/20 0.57
ATM Q13315 1/20 0.57
HDAC3 O15379 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
MAOB P27338 2/20 0.55
LMNA P02545 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
HDAC6 Q9UBN7 1/20 0.54
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
TAS1R3 Q7RTX0 1/20 0.52
TAS1R1 Q7RTX1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL688743 1.00 KMT2A (0.62) KMT2AMEN1MAPTGSK3BF3
SCHEMBL12154213 0.94 POLB (0.62) KMT2AMEN1MAPTGSK3BF3
SCHEMBL26036275 0.89 POLB (0.58) KMT2AMEN1MAPTGSK3BF3
SCHEMBL26036267 0.89 POLB (0.58) KMT2AMEN1MAPTGSK3BF3
SCHEMBL18121572 0.89 KMT2A (0.76) KMT2AMEN1MAPTGSK3BF3
SCHEMBL27989003 0.88 CA12 (0.60) KMT2AMEN1MAPTPOLBMAOB
SCHEMBL12154241 0.86 MAOB (0.56) KMT2AMEN1MAPTGSK3BPOLB
SCHEMBL648890 0.86 KMT2A (0.60) KMT2AMEN1MAPTPOLBMAOB
SCHEMBL22490432 0.84 KMT2A (0.69) KMT2AMEN1MAPTGSK3BF3
SCHEMBL11769170 0.83 MAOB (0.53) KMT2AMEN1MAPTPOLBHDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252273-B2 Ultraviolet absorber LEAD CHEMICAL CO., LTD. (JP) 2012-08-28 US disclosed
EP-2192106-B1 ULTRAVIOLET ABSORBER LEAD CHEM CO LTD (JP) 2012-02-29 EP disclosed
US-20100239508-A1 ULTRAVIOLET ABSORBER LEAD CHEMICAL CO., LTD. (JP) 2010-09-23 US disclosed
EP-2192106-A1 ULTRAVIOLET ABSORBER Lead Chemical Co. Ltd. (JP) 2010-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239508-A1 ULTRAVIOLET ABSORBER UNG, UACA, ABCG2 KMT2A 4596/4885MEN1 3021/4885MAPT 564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.