SCHEMBL648890

SCHEMBL648890

CCc1ccc(C=CC(=O)Oc2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.60
POLB P06746 1/20 0.58
HTR1A P08908 1/20 0.54
RAB9A P51151 4/20 0.52
LMNA P02545 3/20 0.52
NPC1 O15118 3/20 0.52
MAPT P10636 2/20 0.52
HTT P42858 2/20 0.52
MAOB P27338 2/20 0.52
MEN1 O00255 2/20 0.52
KDM4E B2RXH2 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
AKR1B10 O60218 3/20 0.50
AKR1B1 P15121 3/20 0.50
CA12 O43570 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
CA4 P22748 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12154213 0.92 POLB (0.62) KMT2APOLBRAB9ALMNANPC1
SCHEMBL23924318 0.88 KMT2A (0.52) KMT2APOLBHTR1ARAB9ALMNA
SCHEMBL4194922 0.88 KMT2A (0.57) KMT2APOLBHTR1ARAB9ALMNA
SCHEMBL26036275 0.88 POLB (0.58) KMT2APOLBRAB9ALMNANPC1
SCHEMBL26036267 0.88 POLB (0.58) KMT2APOLBRAB9ALMNANPC1
SCHEMBL688743 0.86 KMT2A (0.62) KMT2APOLBRAB9ALMNANPC1
SCHEMBL688742 0.86 KMT2A (0.62) KMT2APOLBRAB9ALMNANPC1
SCHEMBL27989003 0.86 CA12 (0.60) KMT2APOLBRAB9AMAPTMAOB
SCHEMBL27498254 0.86 LMNA (0.55) KMT2APOLBRAB9ALMNANPC1
SCHEMBL12154241 0.84 MAOB (0.56) KMT2APOLBRAB9ALMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12239209-B2 System for dispensing a cosmetic product L'OREAL (FR) 2025-03-04 US claimed
US-20240306688-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2024-09-19 US claimed
EP-4391827-A1 METHOD OF MITIGATING OFF-ODORS Givaudan SA (CH) 2024-07-03 EP claimed
CN-116693393-A Method for purifying phenethyl cinnamate and preparation process thereof 安徽锦戎香料有限公司 2023-09-05 CN claimed
WO-2023025549-A1 METHOD OF MITIGATING OFF-ODORS GIVAUDAN SA (CH) 2023-03-02 WO claimed
US-20220160108-A1 SYSTEM FOR DISPENSING A COSMETIC PRODUCT L'OREAL (FR) 2022-05-26 US claimed
CN-109674667-A A kind of hair washing essence that fragrance retention is lasting 广州积美国际贸易有限公司 2019-04-26 CN claimed
CN-105199851-B A kind of cream odor type flavouring essence for tobacco 河南中烟工业有限责任公司 2019-03-08 CN claimed
CN-108740348-A A kind of sweet citrus type house ox feedstuff flavouring agent and preparation method thereof 成都大帝汉克生物科技有限公司 2018-11-06 CN claimed
EP-3270980-A1 AIR FRESHENING DEVICE Givaudan SA (CH) 2018-01-24 EP claimed
CN-103191782-A Supported solid acid catalyst, and method for preparing ester perfumes through applying it APPLE FLAVOR & FRAGRANCE GROUP CO LTD 2013-07-10 CN claimed
CN-102628229-A Anti-precipitant and its preparation method ZHEJIANG ANOKY AUX Y CO LTD 2012-08-08 CN claimed
EP-2166871-A1 TASTE POTENTIATOR COMPOSITIONS IN ORAL DELIVERY SYSTEMS Cadbury Adams USA LLC (US) 2010-03-31 EP claimed
CN-101633822-A Additive capable of removing bad smell in cigarette lap adhesive and preparation and use methods thereof HONGYUN HONGHE TOBACCO GROUP C 2010-01-27 CN claimed
WO-2008141333-A1 TASTE POTENTIATOR COMPOSITIONS IN ORAL DELIVERY SYSTEMS CADBURY ADAMS USA LLC (US) 2008-11-20 WO claimed
US-20070166341-A1 Solid volatile composition and method and system for making the same INTERNATIONAL ARTS & SCIENCE GROUP, INC. 2007-07-19 US claimed
CN-1572335-A Self-Service respiratory vaccination instrument for SARS infectious disease CONG FANZI (CN) 2005-02-02 CN claimed
CN-1520846-A Quick-effective aerosol with plant aroma and its preparation 丛繁滋 2004-08-18 CN claimed
CN-1500477-A Quick result aerosol with plant aroma and its preparation 丛繁滋 2004-06-02 CN claimed
CN-1475204-A Medicinal Composition, dry powder vapor, nebula, nebula auxiliary preparation for use through mouth and nose and its preparation method 丛繁滋 2004-02-18 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160108-A1 SYSTEM FOR DISPENSING A COSMETIC PRODUCT PDE12, SAMM50, POLR1C KMT2A 1441/4885POLB 60/4885HTR1A 1154/4885
US-12239209-B2 System for dispensing a cosmetic product PDE12, SAMM50, POLR1C KMT2A 1441/4885POLB 60/4885HTR1A 1154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.