Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3356645 | 1.00 | SIGMAR1 (0.53) | SIGMAR1CSNK1EKCNH2ANPEPERAP2 | |
| SCHEMBL4049171 | 1.00 | SIGMAR1 (0.53) | SIGMAR1CSNK1EKCNH2ANPEPERAP2 | |
| SCHEMBL6892570 | 0.95 | SIGMAR1 (0.53) | SIGMAR1CSNK1E | |
| SCHEMBL3356781 | 0.95 | SIGMAR1 (0.53) | SIGMAR1CSNK1E | |
| SCHEMBL4036975 | 0.95 | SIGMAR1 (0.53) | SIGMAR1CSNK1E | |
| SCHEMBL14627960 | 0.92 | CSNK1E (0.53) | CSNK1EANPEPERAP2F2 | |
| SCHEMBL496056 | 0.91 | ANPEP (0.55) | SIGMAR1CSNK1EKCNH2ANPEPERAP2 | |
| SCHEMBL3347864 | 0.91 | ANPEP (0.55) | SIGMAR1CSNK1EKCNH2ANPEPERAP2 | |
| SCHEMBL4044665 | 0.91 | ANPEP (0.55) | SIGMAR1CSNK1EKCNH2ANPEPERAP2 | |
| SCHEMBL4696783 | 0.91 | ANPEP (0.55) | SIGMAR1CSNK1EKCNH2ANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |