Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885251 | 0.99 | CYP4F2 (0.41) | HDAC1HDAC6CYP4F2CYP4A11PPARA | |
| SCHEMBL6155178 | 0.92 | KDM4E (0.42) | HDAC1HDAC6PPARAPPARGKDM4E | |
| SCHEMBL6156490 | 0.91 | KDM4E (0.42) | HDAC1HDAC6PPARAPPARGKDM4E | |
| SCHEMBL6158593 | 0.88 | TUBB1 (0.38) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6156369 | 0.88 | TUBB1 (0.38) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6887534 | 0.86 | LTB4R (0.39) | HDAC1CYP4F2CYP4A11PPARAPPARG | |
| SCHEMBL6158412 | 0.86 | PPARA (0.38) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6885036 | 0.85 | PPARG (0.40) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6154629 | 0.85 | TUBB1 (0.37) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6887229 | 0.83 | KDM4E (0.39) | CYP4F2CYP4A11KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |