Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885036 | 0.97 | PPARG (0.40) | LTB4RLTB4R2PPARGPPARAKDM4E | |
| SCHEMBL6887229 | 0.93 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6156399 | 0.91 | LTB4R (0.48) | LTB4RLTB4R2PPARGPPARAKDM4E | |
| SCHEMBL6155446 | 0.89 | LTB4R (0.44) | LTB4RLTB4R2PPARGPPARAKDM4E | |
| SCHEMBL6155189 | 0.87 | TUBB1 (0.39) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6885251 | 0.87 | CYP4F2 (0.41) | PPARGPPARAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6155581 | 0.86 | KDM4E (0.42) | LTB4RLTB4R2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6154788 | 0.86 | TUBB1 (0.39) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6887502 | 0.86 | HDAC1 (0.41) | PPARGPPARAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6155410 | 0.85 | CHRM2 (0.39) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |