Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880956 | 0.90 | — | — | |
| SCHEMBL6888274 | 0.88 | — | — | |
| SCHEMBL6887056 | 0.86 | MAP3K7 (0.34) | — | |
| SCHEMBL6884998 | 0.84 | GSK3B (0.34) | GSK3B | |
| SCHEMBL7029787 | 0.83 | LMNA (0.31) | GSK3B | |
| SCHEMBL6887745 | 0.83 | LMNA (0.31) | GSK3B | |
| SCHEMBL6880576 | 0.82 | — | — | |
| SCHEMBL6888686 | 0.82 | TK1 (0.31) | — | |
| SCHEMBL6885730 | 0.81 | — | — | |
| SCHEMBL6886773 | 0.81 | GSK3B (0.45) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |