Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031826 | 0.90 | PTPN1 (0.49) | SCN3ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6884890 | 0.88 | PTPN1 (0.43) | SCN3ASCN9ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL6029811 | 0.88 | PTPN1 (0.51) | SCN3ASCN9ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL6888068 | 0.88 | PTPN1 (0.51) | SCN3ASCN9ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL6030700 | 0.88 | PTPN1 (0.51) | SCN3ASCN9ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL6031823 | 0.88 | PTPN1 (0.51) | SCN3ASCN9ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL6887689 | 0.86 | PTPN1 (0.44) | SCN3ASCN9ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL6028026 | 0.83 | KMT2A (0.43) | SCN3ASCN9ARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6028961 | 0.83 | RAB9A (0.46) | SCN3ASCN9ARAB9ALMNASMN1; SMN2 | |
| SCHEMBL6027147 | 0.82 | SCN3A (0.39) | SCN3ASCN9ARAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229927-A1 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | AVANIR PHARMACEUTICALS | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229927-A1 | Imidazole derivatives for treatment of allergic and hyperproliferative disorders | ICOS, TSLP, IKZF3 | SCN3A 4724/4885SCN9A 4847/4885RAB9A 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.