Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883961 | 0.95 | MRGPRX4 (0.55) | MRGPRX4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6566359 | 0.90 | MRGPRX4 (0.66) | MRGPRX4NPC1RAB9ANR4A2MAOB | |
| SCHEMBL6883959 | 0.89 | NPC1 (0.46) | MRGPRX4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6889059 | 0.87 | FFAR1 (0.48) | MRGPRX4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3911336 | 0.86 | MRGPRX4 (0.62) | MRGPRX4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6882555 | 0.86 | MRGPRX4 (0.55) | MRGPRX4NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6566172 | 0.86 | MRGPRX4 (0.63) | MRGPRX4NPC1RAB9ASMN1; SMN2NR4A2 | |
| SCHEMBL6562981 | 0.86 | MRGPRX4 (0.52) | MRGPRX4NPC1RAB9ANR4A2MAOB | |
| SCHEMBL6564903 | 0.85 | MRGPRX4 (0.56) | MRGPRX4NPC1RAB9ANR4A2MAOB | |
| SCHEMBL6564604 | 0.85 | MRGPRX4 (0.56) | MRGPRX4NPC1RAB9ANR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |