Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883847 | 0.92 | MRGPRX4 (0.47) | MRGPRX4NR4A2PTGER4SMPD1MAOB | |
| SCHEMBL6883961 | 0.89 | MRGPRX4 (0.55) | MRGPRX4NR4A2PTGER4SMPD1MAOB | |
| SCHEMBL6566172 | 0.89 | MRGPRX4 (0.63) | MRGPRX4NR4A2PTGER4SMPD1RXRA | |
| SCHEMBL6882555 | 0.87 | MRGPRX4 (0.55) | MRGPRX4NR4A2PTGER4SMPD1MAOB | |
| SCHEMBL6566359 | 0.87 | MRGPRX4 (0.66) | MRGPRX4NR4A2SMPD1MAOBNR1H4 | |
| SCHEMBL6887724 | 0.86 | MRGPRX4 (0.53) | MRGPRX4NR4A2PTGER4SMPD1MAOB | |
| SCHEMBL6564818 | 0.85 | MRGPRX4 (0.54) | MRGPRX4NR4A2NR1H4 | |
| SCHEMBL6563998 | 0.85 | MRGPRX4 (0.53) | MRGPRX4NR4A2PTGER4MAOB | |
| SCHEMBL6564604 | 0.84 | MRGPRX4 (0.56) | MRGPRX4NR4A2PTGER4SMPD1MAOB | |
| SCHEMBL6888101 | 0.82 | MRGPRX4 (0.47) | MRGPRX4NR4A2SMPD1MAOBNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |