Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688979 | 0.90 | NR1H4 (0.47) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL275335 | 0.88 | NR1H4 (0.60) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL687797 | 0.78 | NR1H4 (0.46) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL274417 | 0.78 | NR1H4 (0.62) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL715227 | 0.74 | CDC7 (0.43) | NR1H4KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL687825 | 0.73 | NR1H4 (0.53) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL687997 | 0.73 | NR1H4 (0.53) | NR1H4KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL275298 | 0.72 | NR1H4 (0.73) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL275878 | 0.71 | NR1H4 (0.62) | NR1H4KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL275464 | 0.70 | NR1H4 (0.69) | NR1H4KMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532153-B1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X CEPTOR THERAPEUTICS INC (US) | 2012-02-29 | — | — | EP | claimed |