Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887832 | 1.00 | MRGPRX4 (0.41) | MRGPRX4PKMNR4A2NR4A1NR4A3 | |
| SCHEMBL6155057 | 0.88 | NR4A2 (0.46) | MRGPRX4PKMNR4A2NR4A1NR4A3 | |
| SCHEMBL6155052 | 0.88 | NR4A2 (0.46) | MRGPRX4PKMNR4A2NR4A1NR4A3 | |
| SCHEMBL6155449 | 0.79 | VDR (0.54) | MRGPRX4PKMNR4A2NR4A1NR4A3 | |
| SCHEMBL6155433 | 0.79 | VDR (0.54) | MRGPRX4PKMNR4A2NR4A1NR4A3 | |
| SCHEMBL6155445 | 0.78 | NR4A1 (0.40) | PKMNR4A2NR4A1NR4A3MAOB | |
| SCHEMBL6880160 | 0.77 | FFAR1 (0.42) | MRGPRX4ALOX5AP | |
| SCHEMBL6880164 | 0.77 | FFAR1 (0.42) | MRGPRX4ALOX5AP | |
| SCHEMBL3187183 | 0.74 | CACNA1B (0.47) | MRGPRX4PKMNR4A2NR4A1NR4A3 | |
| SCHEMBL3187190 | 0.74 | CACNA1B (0.47) | MRGPRX4PKMNR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |