Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155057 | 1.00 | NR4A2 (0.46) | NR4A2NR4A1NR4A3MRGPRX4PKM | |
| SCHEMBL6887832 | 0.88 | MRGPRX4 (0.41) | NR4A2NR4A1NR4A3MRGPRX4PKM | |
| SCHEMBL6887830 | 0.88 | MRGPRX4 (0.41) | NR4A2NR4A1NR4A3MRGPRX4PKM | |
| SCHEMBL6155449 | 0.81 | VDR (0.54) | NR4A2NR4A1NR4A3MRGPRX4PKM | |
| SCHEMBL6155433 | 0.81 | VDR (0.54) | NR4A2NR4A1NR4A3MRGPRX4PKM | |
| SCHEMBL6155445 | 0.79 | NR4A1 (0.40) | NR4A2NR4A1NR4A3PKMBCL2 | |
| SCHEMBL3205501 | 0.77 | PKM (0.55) | NR4A2NR4A1NR4A3MRGPRX4PKM | |
| SCHEMBL3205494 | 0.77 | PKM (0.55) | NR4A2NR4A1NR4A3MRGPRX4PKM | |
| SCHEMBL6155559 | 0.76 | FFAR1 (0.43) | NR4A2NR4A1NR4A3MRGPRX4PKM | |
| SCHEMBL6155553 | 0.76 | FFAR1 (0.43) | NR4A2NR4A1NR4A3MRGPRX4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |