Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14016355 | 0.69 | SMN1; SMN2 (0.38) | MAPT | |
| SCHEMBL2691041 | 0.69 | — | — | |
| SCHEMBL4859696 | 0.69 | KDM4E (0.39) | MAPT | |
| SCHEMBL2706623 | 0.69 | SMN1; SMN2 (0.38) | MAPT | |
| SCHEMBL24535432 | 0.69 | — | — | |
| SCHEMBL6234255 | 0.69 | — | — | |
| SCHEMBL50791 | 0.67 | GAA (0.39) | — | |
| SCHEMBL15200349 | 0.67 | — | — | |
| SCHEMBL24535427 | 0.65 | — | — | |
| SCHEMBL24535421 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |
| US-20030187256-A1 | Benoxazinones/benzothiazinones as serine protease inhibitors | BERRYMAN KENT ALAN (US) | 2003-10-02 | — | — | US | claimed |
| US-6509335-B1 | This invention discloses benzoxazinone and benzothiazinone compounds which display inhibitory effects on serine proteases such as factor Xa, thrombin, and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts of | WARNER-LAMBERT COMPANY | 2003-01-21 | — | — | US | claimed |
| US-20020086866-A1 | Quinoxalinones as serine protease inhibitors | DUDLEY DANETTE ANDREA (US) | 2002-07-04 | — | — | US | claimed |
| US-6410536-B1 | ANTICOAGULANTS | WARNER-LAMBERT COMPANY | 2002-06-25 | — | — | US | claimed |
| EP-1091955-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-04-18 | — | — | EP | claimed |
| EP-1068191-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-17 | — | — | EP | claimed |
| EP-1068190-A1 | QUINOXALINONES AS SERINE PROTEASE INHIBITORS SUCH AS FACTOR XA AND THROMBIN | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999050254-A1 | QUINOXALINONES AS SERINE PROTEASE INHIBITORS SUCH AS FACTOR XA AND THROMBIN | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | claimed |
| WO-1999050257-A1 | BENZOXAZINONES/BENZOTHIAZINONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | claimed |
| WO-1999050263-A1 | QUINOLONES AS SERINE PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1999-10-07 | — | — | WO | claimed |
| US-5698683-A | Mixed aluminium-heavy metal dyestuff complexes and a process for their preparation | CLARIANT FINANCE (BVI) LIMITED (BG) | 1997-12-16 | — | — | US | claimed |
| US-11021585-B2 | Light stabilized polyolefin films, tapes and monofilaments | BASF SE (DE) | 2021-06-01 | — | — | US | disclosed |
| US-20200223996-A1 | LIGHT STABILIZED POLYOLEFIN FILMS, TAPES AND MONOFILAMENTS | BASF SE (DE) | 2020-07-16 | — | — | US | disclosed |
| US-10689495-B2 | Light stabilized polyolefin films, tapes and monofilaments | BASF SE (DE) | 2020-06-23 | — | — | US | disclosed |
| EP-3473670-B1 | LIGHT STABILIZED POLYOLEFIN FILMS, TAPES AND MONOFILAMENTS | BASF SE (DE) | 2020-04-15 | — | — | EP | disclosed |
| US-5719217-A | COMPRISING AT LEAST TWO DIFFERENT POLYMERIC POLYALKYLPIPERIDINE DERIVATIVES | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| US-5698683-A | Mixed aluminium-heavy metal dyestuff complexes and a process for their preparation | CLARIANT FINANCE (BVI) LIMITED (BG) | 1997-12-16 | — | — | US | disclosed |
| US-4863981-A | POLYMERS CONTAINING POLYALKYLPIPERDINE GROUPS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4168981-A | Bis(substituted amino)sulfides as reversible inhibitor sources for photopolymerization | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086866-A1 | Quinoxalinones as serine protease inhibitors | HABP2, SERPINB1, PRSS1 | ALDH1A1 1960/4885POLB 4509/4885MAPT 4000/4885 |
| US-20030187256-A1 | Benoxazinones/benzothiazinones as serine protease inhibitors | HABP2, SPINT2, SERPINB1 | ALDH1A1 2444/4885POLB 4517/4885MAPT 3606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.