Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847059 | 0.86 | KDM4E (0.36) | KDM4ELMNACYP2C19CRBNMAPT | |
| SCHEMBL5573151 | 0.78 | KDM4E (0.32) | KDM4ELMNACYP2C19CRBN | |
| SCHEMBL2691041 | 0.77 | — | — | |
| SCHEMBL14016355 | 0.77 | SMN1; SMN2 (0.38) | KDM4ELMNACYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL2706623 | 0.77 | SMN1; SMN2 (0.38) | KDM4ELMNACYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL15118760 | 0.74 | LMNA (0.35) | KDM4ELMNACYP2C19 | |
| SCHEMBL578932 | 0.74 | GAA (0.35) | CYP2C19CRBNTSHR | |
| SCHEMBL15278726 | 0.73 | TRIM24 (0.41) | CRBN | |
| Iodide SCHEMBL6292630 | 0.72 | GAA (0.34) | CYP2C19TSHR | |
| Hydrochloric Acid SCHEMBL11333509 | 0.72 | GAA (0.34) | CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368717-B1 | 5-BENZYLIDENE 3-OXA CYCLOPENTANONE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE IN COSMETIC COMPOSITIONS TO PROTECT THE SKIN AND THE HAIR AGAINST SUN RADIATION | L'OREAL (FR) | 1993-01-20 | — | — | EP | claimed |
| CN-108473518-B | Bisphosphonic acid compounds | 株式会社富士药品 | 2021-07-06 | — | — | CN | disclosed |
| US-10689408-B2 | Bisphosphonic acid compound | FUJIYAKUHIN CO., LTD. (JP) | 2020-06-23 | — | — | US | disclosed |
| US-10385069-B2 | Imidazo[2,1-B]thiazole and 5,6-dihydroimidazo[2,1-B]thiazole derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB (SE) | 2019-08-20 | — | — | US | disclosed |
| US-20190002482-A1 | NOVEL BISPHOSPHONIC ACID COMPOUND | FUJIYAKUHIN CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| EP-3409679-A1 | NOVEL BISPHOSPHONIC ACID COMPOUND | Fuji Yakuhin Co., Ltd. (JP) | 2018-12-05 | — | — | EP | disclosed |
| US-20180282348-A1 | IMIDAZO[2,1-B]THIAZOLE AND 5,6-DIHYDROIMIDAZO[2,1-B]THIAZOLE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2018-10-04 | — | — | US | disclosed |
| EP-1698620-B1 | BENZENE COMPOUNDS DISUBSTITUTED WITH CYCLIC GROUPS AT THE 1- AND 2-POSITIONS | EISAI R&D MAN CO LTD (JP) | 2016-09-28 | — | — | EP | disclosed |
| WO-2016042172-A1 | IMIDAZO[2,1-B]THIAZOLE AND 5,6-DIHYDROIMIDAZO[2,1-B]THIAZOLE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2016-03-24 | — | — | WO | disclosed |
| US-8501961-B2 | HIV protease inhibitors and methods for using | PURDUE RESEARCH FOUNDATION (US) | 2013-08-06 | — | — | US | disclosed |
| EP-0400409-A2 | Aromatic copolyetherketones | BAYER AG (DE) | 1990-12-05 | — | — | EP | disclosed |
| EP-0393454-A2 | Heat-resistant polycarbonate moulding composition | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4964890-A | GAS-PERMEABLE FILMS OF A THERMOPLASTIC POLYETHER HAVING DIHYDROXYBENZOPHENONE AND DIHYDROXYDIPHENYLCYCLOALKANE UNITS; DIMENSIONAL STABILITY; HEAT RESISTANCE; MEMBRANES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| EP-0365917-A1 | Polymer mixtures | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0365916-A1 | Polymer mixtures | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0364741-A1 | Aromatic polyetherketones | BAYER AG (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0362603-A1 | Aromatic Polyethersulfones | BAYER AG (DE) | 1990-04-11 | — | — | EP | disclosed |
| US-4900754-A | ANTICHOLESTEROL AGENTS | RORER PHARMACEUTICAL CORP. (US) | 1990-02-13 | — | — | US | disclosed |
| US-4863957-A | ANTICHOLESTEROL AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| WO-1989005639-A1 | NOVEL HMG-CoA REDUCTASE INHIBITORS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282348-A1 | IMIDAZO[2,1-B]THIAZOLE AND 5,6-DIHYDROIMIDAZO[2,1-B]THIAZOLE DERIVATIVES USEFUL AS S100-INHIBITORS | S100B, S100P, S100A4 | KDM4E 3946/4885LMNA 4388/4885CYP2C19 4377/4885 |
| US-10385069-B2 | Imidazo[2,1-B]thiazole and 5,6-dihydroimidazo[2,1-B]thiazole derivatives useful as S100-inhibitors | S100B, S100P, S100A4 | KDM4E 3946/4885LMNA 4388/4885CYP2C19 4377/4885 |
| US-10689408-B2 | Bisphosphonic acid compound | SOST, PTH1R, BMP2 | KDM4E 3461/4885LMNA 4644/4885CYP2C19 2391/4885 |
| US-20190002482-A1 | NOVEL BISPHOSPHONIC ACID COMPOUND | SOST, PTH1R, BMP2 | KDM4E 3600/4885LMNA 4724/4885CYP2C19 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.