Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11693475 | 0.90 | SLC6A2 (0.63) | SLC6A4SLC6A3SLC6A2MAOAMAOB | |
| SCHEMBL151540 | 0.90 | ESR1 (0.52) | SLC6A4SLC6A3SLC6A2NR3C2MAOA | |
| SCHEMBL9069704 | 0.85 | ESR1 (0.61) | SLC6A4SLC6A3SLC6A2MAOAMAOB | |
| SCHEMBL535702 | 0.85 | TAAR1 (0.56) | SLC6A4SLC6A3SLC6A2MAOAESR1 | |
| SCHEMBL8983689 | 0.85 | TAAR1 (0.56) | SLC6A4SLC6A3SLC6A2MAOAESR1 | |
| SCHEMBL14799062 | 0.85 | TAAR1 (0.56) | SLC6A4SLC6A3SLC6A2MAOAESR1 | |
| Ammonia Solution, Strong SCHEMBL5082413 | 0.83 | TAAR1 (0.54) | SLC6A4SLC6A3SLC6A2MAOAESR1 | |
| Methylamine SCHEMBL5328370 | 0.81 | TAAR1 (0.58) | SLC6A4SLC6A3SLC6A2MAOAESR1 | |
| Hydrochloric Acid SCHEMBL7266799 | 0.81 | TAAR1 (0.52) | SLC6A4SLC6A3SLC6A2MAOAESR1 | |
| SCHEMBL29167634 | 0.81 | SLC6A3 (0.88) | SLC6A4SLC6A3SLC6A2NR3C2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023171697-A1 | PRODUCTION METHOD FOR FLUORINE-CONTAINING COMPOUND | ＡＧＣ株式会社 | 2023-09-14 | — | — | WO | disclosed |
| EP-0770065-B1 | TRI-SUBSTITUTED PHENYL DERIVATES USEFUL AS PDE IV INHIBITORS | CELLTECH R&D LTD (GB) | 2004-03-31 | — | — | EP | disclosed |
| US-6077854-A | Tri-substituted phenyl derivatives and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED (GB) | 2000-06-20 | — | — | US | disclosed |
| US-5786354-A | Tri-substituted phenyl derivatives and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED (GB) | 1998-07-28 | — | — | US | disclosed |
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4062960-A | Hypolipidemic alkenesulfonamides | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |