Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675875 | 0.83 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL10969531 | 0.78 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL10677538 | 0.78 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL10968713 | 0.76 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL13997161 | 0.76 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL10731210 | 0.75 | MEN1 (0.67) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL10679854 | 0.74 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL10682396 | 0.74 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1RAB9ANPC1LMNA | |
| SCHEMBL3300574 | 0.74 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1RAB9ANPC1TSHR | |
| SCHEMBL10973437 | 0.73 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |