Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | MIF | P14174 | 4/20 | 0.47 |
| ▸ | NAAA | Q02083 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethane SCHEMBL28176599 | 0.85 | MIF (0.50) | MIFNAAAMAOBMAOATSHR | |
| SCHEMBL4332687 | 0.83 | NAAA (0.68) | MIFNAAAMAOBMAOATRPA1 | |
| SCHEMBL1006435 | 0.83 | NAAA (0.68) | MIFNAAAMAOBMAOATRPA1 | |
| SCHEMBL11240241 | 0.83 | NAAA (0.68) | MIFNAAAMAOBMAOATRPA1 | |
| SCHEMBL380832 | 0.83 | NAAA (0.68) | MIFNAAAMAOBMAOATRPA1 | |
| Benzylamine SCHEMBL25166822 | 0.81 | LOXL2 (0.56) | LOXL2MIFMAOBTAAR1CYP1A2 | |
| SCHEMBL425325 | 0.81 | MIF (0.67) | MIFNAAAMAOBMAOAKEAP1 | |
| Biphenyl SCHEMBL2353895 | 0.80 | NAAA (0.44) | MIFNAAAMAOBMAOATAAR1 | |
| Diphenylmethane SCHEMBL3882710 | 0.80 | NAAA (0.46) | MIFNAAAMAOBMAOATSHR | |
| SCHEMBL1149239 | 0.79 | MIF (0.66) | MIFNAAAMAOBMAOAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641888-B1 | AMINO ACID DERIVATIVES AND THEIR USE AS A SAG CONTROL AGENT | NUPLEX RESINS BV (NL) | 2012-02-29 | — | — | EP | disclosed |
| US-7576151-B2 | Amino acid derivatives and their use as a sag control agent | NUPLEX RESINS, B.V. (NL) | 2009-08-18 | — | — | US | disclosed |
| CN-100471918-C | Carbon-substituted methyl amine derivatives and their use as a rheology control agent | NUPLEX RESINS BV (NL) | 2009-03-25 | — | — | CN | disclosed |
| US-20060223954-A1 | Amino acid derivatives and their use as a sag control agent | ALLNEX NETHERLANDS B.V. (NL) | 2006-10-05 | — | — | US | disclosed |
| CN-1816597-A | amino acid derivatives and their use as sag control agents | BRINKHUIS RICHARD HENDRIKUS GE (NL) | 2006-08-09 | — | — | CN | disclosed |