Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 6/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 6/20 | 0.40 |
| ▸ | NPY1R | P25929 | 5/20 | 0.40 |
| ▸ | NPY2R | P49146 | 4/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887132 | 0.92 | NPY4R (0.48) | MAOBDRD4NPY4RNPY1RNPY2R | |
| Arginine SCHEMBL19410729 | 0.78 | CA12 (0.44) | MAOBDRD4DRD3CA12CA1 | |
| Arginine SCHEMBL19410730 | 0.78 | CA12 (0.44) | MAOBDRD4DRD3CA12CA1 | |
| SCHEMBL30905443 | 0.78 | NPY4R (0.55) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7260360 | 0.78 | PTGER4 (0.52) | — | |
| Water SCHEMBL8529560 | 0.77 | SPHK1 (0.48) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7416564 | 0.77 | MMP2 (0.48) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7530376 | 0.77 | MMP2 (0.48) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7530381 | 0.77 | MMP2 (0.48) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL4796989 | 0.76 | MAOB (0.46) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401818-A2 | TARGETED MULTIVALENT MACROMOLECULES | Targesome, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002096367-A2 | TARGETED MULTIVALENT MACROMOLECULES | TARGESOME, INC. (US) | 2002-12-05 | — | — | WO | disclosed |