Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3313721 | 0.94 | RAB9A (0.37) | RAB9ANPC1TP53TSHRSMN1; SMN2 | |
| SCHEMBL14010474 | 0.92 | RAB9A (0.36) | RAB9ANPC1TP53TSHRSMN1; SMN2 | |
| SCHEMBL1869939 | 0.92 | RAB9A (0.36) | RAB9ANPC1TP53TSHRSMN1; SMN2 | |
| SCHEMBL2355414 | 0.87 | MEN1 (0.47) | RAB9ANPC1TP53TSHRSMN1; SMN2 | |
| SCHEMBL3966184 | 0.86 | RAPGEF4 (0.38) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12457752 | 0.86 | MEN1 (0.37) | RAB9ANPC1TP53TSHRSMN1; SMN2 | |
| SCHEMBL3303729 | 0.86 | AR (0.36) | RAB9ANPC1TP53TSHRSMN1; SMN2 | |
| SCHEMBL2356139 | 0.85 | MEN1 (0.36) | RAB9ANPC1TP53TSHRSMN1; SMN2 | |
| SCHEMBL3332556 | 0.85 | ALDH1A1 (0.34) | RAB9ANPC1TP53TSHRSMN1; SMN2 | |
| SCHEMBL3339528 | 0.85 | SLC2A1 (0.39) | MEN1KMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014166-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-2014165-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-2014167-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-2011397-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-07 | — | — | EP | claimed |
| EP-2011396-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-07 | — | — | EP | claimed |
| EP-2011395-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-07 | — | — | EP | claimed |
| EP-1775290-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-7795258-B2 | Pyridazine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-14 | — | — | US | disclosed |
| US-7795258-B2 | Pyridazine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-09-14 | — | — | US | disclosed |
| EP-2014166-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-2014167-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-2014165-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |
| EP-2011397-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-07 | — | — | EP | disclosed |
| EP-2011396-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-07 | — | — | EP | disclosed |
| EP-2011395-A1 | Active compound combinations | Bayer CropScience AG (DE) | 2009-01-07 | — | — | EP | disclosed |
| US-20080275050-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| US-20080275050-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-11-06 | — | — | US | disclosed |
| EP-1775290-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2007-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275050-A1 | Pyridazine Compound and Use Thereof | CYP4Z1, PNPO, PLPBP | RAB9A 1132/4885NPC1 1625/4885TP53 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.