Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TK2 | O00142 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27945886 | 0.85 | LMNA (0.40) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL292198 | 0.85 | LMNA (0.45) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL15893327 | 0.84 | TK1 (0.44) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL16099482 | 0.84 | TK1 (0.44) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL1583331 | 0.84 | TK1 (0.44) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL6025793 | 0.83 | TK1 (0.43) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL18039264 | 0.83 | TK1 (0.43) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL6025787 | 0.83 | TK1 (0.43) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL12482651 | 0.82 | TK1 (0.45) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL4745548 | 0.82 | TK1 (0.43) | TK1LMNASMN1; SMN2TK2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425417-A2 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | Clondiag Chip Technologies GmbH (DE) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003018838-A2 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2003-03-06 | — | — | WO | disclosed |