Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPOR | P19235 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGAV | P06756 | 5/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676093 | 0.95 | SMN1; SMN2 (0.34) | SMN1; SMN2EPORBCHECNR2AVPR1B | |
| SCHEMBL6892894 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2EPORAVPR1BHPGDMEN1 | |
| SCHEMBL4955666 | 0.88 | MMP2 (0.42) | SMN1; SMN2ITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL7667809 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2EPORAVPR1BHPGDMEN1 | |
| SCHEMBL14271433 | 0.83 | MAPT (0.40) | SMN1; SMN2HPGDMEN1KMT2ACA12 | |
| SCHEMBL4654777 | 0.83 | MAPT (0.40) | SMN1; SMN2HPGDMEN1KMT2ACA12 | |
| SCHEMBL27608126 | 0.83 | MMP2 (0.43) | HPGDITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL4381805 | 0.83 | MMP2 (0.43) | HPGDITGB3ITGAVITGA2BITGB1 | |
| SCHEMBL6888752 | 0.80 | MMP2 (0.44) | — | |
| SCHEMBL8313513 | 0.78 | SYK (0.42) | HPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683163-B2 | MONITORING ANGIOGENESIS FACTOR | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-01-27 | — | — | US | disclosed |